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35 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27050713 5 Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists.EBI The Scripps Research Institute
26422006 13 Inhibiting the Inflammasome: A Chemical Perspective.EBI The University of Manchester
26010811 19 Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists.EBI National Institute of Health
25268544 12 Trehalose- and glucose-derived glycoamphiphiles: small-molecule and nanoparticle Toll-like receptor 4 (TLR4) modulators.EBI University of Sevilla
25252784 3 Development ofaGlcN(1¿1)aMan-based lipid A mimetics as a novel class of potent Toll-like receptor 4 agonists.EBI University of Natural Resources and Life Sciences
24471857 47 Euodenine A: a small-molecule agonist of human TLR4.EBI Griffith University
24177366 3 Novel toll-like receptor 4 (TLR4) antagonists identified by structure- and ligand-based virtual screening.EBI Blood Transfusion Centre of Slovenia
16377188 12 Novel endotoxin-sequestering compounds with terephthalaldehyde-bis-guanylhydrazone scaffolds.EBI University of Kansas
22985959 26 Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors.EBI University of Colorado At Boulder
21936536 7 Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.EBI Industrial Research
21591694 34 Development ofß-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics.EBI University of Colorado At Boulder
18835160 2 The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.EBI Glaxosmithkline
18828583 29 Small molecule modulators of toll-like receptors.EBI Schering-Plough Research Institute
16236498 14 Toll-like receptor 2 antagonists. Part 1: preliminary SAR investigation of novel synthetic phospholipids.EBI Eisai Research Institute
32944143 89 Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9).EBI Princ
32786235 87 Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay.EBI Genomics Institute of The Novartis Research Foundation
32071680 5 Design and Catalyzed Activation of Tak-242 Prodrugs for Localized Inhibition of TLR4-Induced Inflammation.EBI Baylor University
31265286 17 Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[EBI Glaxosmithkline
31283217 8 Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model.EBI Ajou University
31188592 39 Why Some Targets Benefit from beyond Rule of Five Drugs.EBI Boston University
30998353 10 Discovery of 3-(Indol-5-yl)-indazole Derivatives as Novel Myeloid Differentiation Protein 2/Toll-like Receptor 4 Antagonists for Treatment of Acute Lung Injury.EBI Wenzhou Medical University
29472126 36 Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout.EBI Soochow University
29807331 19 Discovery of novel small molecule TLR4 inhibitors as potent anti-inflammatory agents.EBI School of Pharmaceutical Sciences
29494148 10 Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.EBI University of Milano-Bicocca
28506585 8 CEBI Guizhou University
29049886 62 Structure-Activity Relationship Studies of Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands.EBI University of California
28537730 9 Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities.EBI University of Colorado Boulder